Overview of Granular Cell Tumor General Hospitals in Iraq over 11-years
DOI:
https://doi.org/10.47577/biochemmed.v9i.11419Keywords:
Granular cell tumor, oral cavity, metastatic cancer lesions, clinicopathological aspectsAbstract
Granular cell tumor is rare tumors from Schwann cells with clinicopathological feature results, which may be showed in both benign and malignant tumor. Several tumors commonly appear in the oral cavity, gastrointestinal tract and skin. This must be appropriately treated to avoid repetition or metastatic cancer lesions. The aim study is to search clinicopathological aspects of granular cell tumor diagnosed at different general hospitals in Iraq and to compare these findings with epidemiological findings from different governorates positions. The data was collected from different Iraq governorates in mouth and tongue area from 2010 to 2020 years. Different parameters were displayed like age group, gender, topography, morphology and distribution of annual patients of the tumor. According to the available of the all information about these characteristics was revealed the inclusion criteria. The factors frequencies were calculated from descriptive analysis of the data. The total (101) cases of granular cell tumor in mouth and tongue location were found. (17) cases was the maximum value in 2015 year and it followed by (15) cases in 2019 year as compared to other years. Baghdad governorate (95) cases has a greatly patients than other governorates. (59) Cases with (58.40 %) of female gender and (42) cases with (41.60) of male and the female to male ratio was (1.38:1).
References
Fisher ER, Wechsler H. Granular cell myoblastoma—a misnomer. Electron microscopic and histochemical evidence concerning its Schwann cell derivation and nature (granular cell schwannoma). Cancer. 1962;15(5):936-54.
Rekhi B, Jambhekar NA. Morphologic spectrum, immunohistochemical analysis, and clinical features of a series of granular cell tumors of soft tissues: a study from a tertiary referral cancer center. Annals of diagnostic pathology. 2010;14(3):162-7.
Musha A, Ogawa M, Yokoo S. Granular cell tumors of the tongue: fibroma or schwannoma. Head & face medicine. 2018;14:1-7.
Stewart CM, Watson RE, Eversole L, Fischlschweiger W, Leider AS. Oral granular cell tumors: a clinicopathologic and immunocytochemical study. Oral surgery, oral medicine, oral pathology. 1988;65(4):427-35.
Serpa MS, Costa-Neto H, de Oliveira PT, da Silveira ÉJD, de Medeiros AMC. Granular cell tumor in two oral anatomic sites. European Archives of Oto-Rhino-Laryngology. 2016;273:3439-41.
Mejía H, Rubiano MFO, Osorio VLD, González MI. S100 negative granular cell tumor of the oral cavity: dermoscopy and surgical approach. Anais brasileiros de dermatologia. 2019;94:79-81.
Scala WAR, Fernandes AMF, Duprat AdC, Costa HOO. Granular cell tumor of the larynx in children: a case report. Revista Brasileira de Otorrinolaringologia. 2008;74:780-5.
Park JY, Hwang JJ, Am Lee S, Lee WS, Kim YH, Chee HK, et al. Granular cell tumor occurring in the chest wall: A case report. The Korean Journal of Thoracic and Cardiovascular Surgery. 2012;45(3):196.
Jhingran A, Russell AH, Seiden MV, Duska LR, Goodman A, Lee SL, et al. Cancers of the cervix, vulva, and vagina. Abeloff's Clinical Oncology: Elsevier; 2020. p. 1468-507. e8.
Etemadi Sh M, Razavi SM, Ghazavi O, Nikbakht MH. Granular cell odontogenic tumor: rep of a rare case and a review of literature. BMC Oral Health. 2022;22(1):1-6.
Chang JY-F, Hwang M-J, Sun A, Chiang C-P. Granular cell tumor: case report. Journal of Dental Sciences. 2021;16(3):1018.
Regezi JA, Sciubba J, Jordan RC. Oral pathology: clinical pathologic correlations: Elsevier Health Sciences; 2016.
Lv X, Sun X, Zhou J, Zhang Y, Lv G. Granular cell tumor of the appendix: a case report and literature review. Journal of International Medical Research. 2022;50(7):03000605221109369.
Maymone MB, Greer RO, Burdine LK, Dao-Cheng A, Venkatesh S, Sahitya PC, et al. Benign oral mucosal lesions: Clinical and pathological findings. Journal of the American Academy of Dermatology. 2019;81(1):43-56.
Barrantes PC, Zhou P, MacDonald SM, Ioakeim-Ioannidou M, Lee NG. Granular cell tumor of the orbit: review of the literature and a proposed treatment modality. Ophthalmic Plastic & Reconstructive Surgery. 2022;38(2):122-31.
Shi Y, Chai N, Zhong L, Li L, Zou J, Xiang J, et al. Experience with esophageal granular cell tumors: clinical and endoscopic analysis of 22 cases. Digestive Diseases and Sciences. 2021;66:1233-9.
Mobarki M, Dumollard JM, Dal Col P, Camy F, Peoc'h M, Karpathiou G. Granular cell tumor a study of 42 cases and systemic review of the literature. Pathology-Research and Practice. 2020;216(4):152865.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Raid Razak Ali AL-Kafaji, Thaer Kassim Ali

This work is licensed under a Creative Commons Attribution 4.0 International License.