Identification Of Plasma Serotonin And Adiponectin As Predictor Biomarkers For Early Detection Of Breast Cancer Among Karbala Province
DOI:
https://doi.org/10.47577/technium.v25i.11944Keywords:
Breast Cancer, Serotonin, And Adiponectin HormonesAbstract
Breast Malignancy Is The Most Common Malignancy Among Women, Constituting Eighteen Percent Of All Cancer Diagnoses In Females. It Is The Seventh Leading Cause Of Cancer-Related Fatalities Worldwide. The Goal Of This Research Is To Find Out How Breast Cancer Patients And Healthy People's Levels Of The Hormones Serotonin (St) And Adiponectin (Adp) Compare. A Group Of 85 People With Breast Cancer And 85 People Who Appeared To Be In Good Health Had Their Serum Concentrations Of The Hormones Serotonin (St) And Adiponectin (Adp) Measured. When Compared To The Control Group, Breast Cancer Patients' Serum Levels Of The Hormones Serotonin (St) And Adiponectin (Adp) Were Significantly Lower (P ≤ 0.05). In Comparison To Healthy Controls, Breast Cancer Patients Have Substantially Reduced Levels Of The Hormones Serotonin (St) And Adiponectin (Adp).
References
Sun, Y. S., Zhao, Z., Yang, Z. N., Xu, F., Lu, H. J., Zhu, Z. Y., ... & Zhu, H. P. (2017). Risk Factors And Preventions Of Breast Cancer. International Journal Of Biological Sciences, 13(11), 1387.
Waks, A. G., & Winer, E. P. (2019). Breast Cancer Treatment: A Review. Jama, 321(3), 288-300.
Sarrouilhe D., Clarhaut J., Defamie N., And Mesnil M. (2015). Serotonin And Cancer: What Is The Link? Current Molecular Medicine 15: 62-77.
Mohammad‐Zadeh, L. F., Moses, L., & Gwaltney‐Brant, S. M. (2008). Serotonin: A Review. Journal Of Veterinary Pharmacology And Therapeutics, 31(3), 187-199.
Gu, L., Cao, C., Fu, J., Li, Q., Li, D. H., & Chen, M. Y. (2018). Serum Adiponectin In Breast Cancer: A Meta-Analysis. Medicine, 97(29), E11433.
Sharma, G. N., Dave, R., Sanadya, J., Sharma, P., & Sharma, K. (2010). Various Types And Management Of Breast Cancer: An Overview. Journal Of Advanced Pharmaceutical Technology & Research, 1(2), 109-126
Smolarz, B., Nowak, A. Z., & Romanowicz, H. (2022). Breast Cancer—Epidemiology, Classification, Pathogenesis And Treatment (Review Of Literature). Cancers, 14(10), 2569.
Rojas, K., & Stuckey, A. (2016). Breast Cancer Epidemiology And Risk Factors. Clinical Obstetrics And Gynecology, 59(4), 651-672.
Jones, L. A., Sun, E. W., Martin, A. M., & Keating, D. J. (2020). The Ever-Changing Roles Of Serotonin. The International Journal Of Biochemistry & Cell Biology, 125, 105776.
Gwynne, W. D., Shakeel, M. S., Girgis-Gabardo, A., & Hassell, J. A. (2021). The Role Of Serotonin In Breast Cancer Stem Cells. Molecules, 26(11), 3171.
Nabablou M., Palasamudram K., And Jamil K. (2014). Adiponectin And Lepting Molecular Actions And Clinical Significance In Breast Cancer, Ijhoscr International Journal Of Hematology-Oncology And Stem Cell Research.
Jardé, T., Perrier, S., Vasson, M. P., & Caldefie-Chézet, F. (2011). Molecular Mechanisms Of Leptin And Adiponectin In Breast Cancer. European Journal Of Cancer, 47(1), 33-43.
Grossmann, M. E., Nkhata, K. J., Mizuno, N. K., Ray, A., & Cleary, M. P. (2008). Effects Of Adiponectin On Breast Cancer Cell Growth And Signaling. British Journal Of Cancer, 98(2), 370-379.
Tabaan D., Saleh E., Hashim Z., And Kamal Z. (2014): Association Of Serum Adiponectin And Leptin Levels With Breast Cancer In Iraqi Women, American Journal Of Pharmacological Sciences.
Tao, Z., Shi, A., Lu, C., Song, T., Zhang, Z., & Zhao, J. (2015). Breast Cancer: Epidemiology And Etiology. Cell Biochemistry And Biophysics, 72, 333-338.
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Copyright (c) 2024 Zahraa Abduladheem Almaialy, Muna Ali Hussein, Z. Abdul Alamir Mezher
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